←   About Deep Origin

Natalie Ma, Ph.D.

Head of Business Development

Natalie Ma, PhD, is Head of Business Development at Deep Origin. A synthetic biologist by training with a PhD in Molecular Biology from Yale, she previously co-founded and led business and clinical development at Felix Biotechnology on phage therapies and has helped build and advise companies in drug discovery across therapeutic areas. Her work focuses on translating advanced computational and experimental tools into impactful therapeutics and enabling teams to navigate the complexities of modern drug development.

Selected Literature

  1. Nangle, S.N., Wolfson, M.Y., Hartsough, L., Ma, N.J., Mason, C.E., Merighi, M., Nathan, V., Silver, P.A., Simon, M., Swett, J., Thompson, D.B., Ziesack, M. The case for biotech on Mars. Nature Biotechnology, 38, 401–407.
  2. Ma, N.J., Hemez, C.F., Barber, K.W., Rinehart, J., Isaacs, F.J. Organisms with alternative genetic codes resolve unassigned codons via mistranslation and ribosomal rescue. eLife 7, e34878.
  3. Ma, N.J., Isaacs, F.J. Genomic Recoding Broadly Obstructs the Propagation of Horizontally Transferred Genetic Elements. Cell Systems 3, 199 – 207.
  4. Pirman, N.L, Barber, K., Aerni, H., Ma, N.J., Haimovich, A.D., Rogulina, S., Isaacs, F.J., Rinehart, J. A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation. Nature Communications 6, 8130.
  5. Amiram, M.A., Haimovich, A.D., Fan, C., Wang, Y.S., Moonan, D.W., Ma, N.J., Rovner, A.J., Nakamura, A., Söll, D., Isaacs, F.J. Evolution of translation machinery in recoded bacteria enables multi-site incorporation of nonstandard amino acids. Nature Biotechnology 33, 1272-9.